Still caught in a relentless conspiracy to capture him by a mysterious clandestine organization, the indomitable Hulk faces off against a new array of powerful abominations. Aided only by his old friend and foe, Doc Samson, and his mysterious benefactor - the enigmatic Mr. Blue (whose identity is at last revealed in its entirety) - the Hulk must fight to save both his life and reputation.

Collects Hulk Smash (2001) #1-2. There's something big and nasty in the desert, and it's cutting a bloody swath toward Dr. Bruce Banner - the man also known as the Incredible Hulk! As Banner marshals the monster within for his ultimate battle, he must be ready to confront a creature with intimate knowledge of his very soul.

On the run...from the police...the government...clandestine forces with an agenda all their own...and the unbridled beast within, Dr. Bruce Banner knows the dread of the hunted. Now he faces the most unimaginable horror of all: a relentless, unkillable pursuer who knows all his weaknesses and will stop at nothing to bring him down.